Adom Koo Mixture

22.00

Sold By: GMF Store
6 sold in last 14 hours

Adom Koo Mixture is for effective relief of constipation, piles, waist pains and removal of excess phlegm. It may also improve eyesight.

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Adom Koo Mixture 22.00 Sold By: GMF Store
     
Total Price: 46.00

Ingredient

Piper guineense

Khaya senegalensis

Indications

Constipation

Waist pains

Colon cleansing

Dosage form

Liquid

Dosage

Adult: Four tablesponful twice daily

Caution

Not recommended for pregnant women, lactating mothers and children below 12 years of age

 

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    Clinical data
    Administration of a leaf decoction to a 49-year-old female diabetic patient caused her fasting blood sugar level to fall from 242 mg/dl to about 120 mg/dl after 12 weeks, remaining at this level for eight weeks (Addae-Mensah, 1992). A 45-year old hypertensive woman, who had diabetes diagnosed on routine examination had her fasting blood sugar level of 370 mg/dl reduced to 250 mg/dl after one week and continued to fall until it normalized after eleven weeks on immediate administration of B. ferruginea. No medication was prescribed for her hypertension, but her blood pressure fell from 180/90 to 140/90 during the treatment period (Addae-Mensah, 1992; Ampofo, 1977). Aqueous extracts of the leaves were able to normalize the fasting blood glucose levels and helped in eliminating glycosuria of patients with maturity-onset diabetes (Iwu, 1993).

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    Neem extracts have shown potential hypoglycaemic properties. Oral administration of the leaf
    extracts reduced blood sugar levels in normal and streptozocin-induced of diabetic models, with the
    hypoglycaemic effect comparable to glibenclamide (Khosla et al., 2000). The leaf extract blocked
    the effects of adrenaline on glucose metabolism and reduced peripheral glucose utilization in
    diabetic and normal rats (Chattopadhyay, 1996).

    The anti-inflammatory properties of the plant have also been demonstrated in various studies. The water-soluble part of the alcoholic leaf extract showed anti-inflammatory activity in the cotton pellet granuloma assay in vivo (Chattopadhway, 1998). Neem extracts have shown a dose-dependent anti-gastric ulcer activity in stressed rats. The extracts also caused a decrease in ethanol-induced gastric mucosal damage, an increase in the amount of adherent gastric mucus in stressed animals, and showed significant anti-histaminic potential (Garg et al., 1993). Bandyopadhyay et al (2002) have investigated the gastroprotective properties of the stem bark extract of A. indica. The gastroprotective effect was attributed to the ability to inhibit acid secretion via blockage of H+/K+-ATPase activity as well as the inhibition of oxidative damage of the gastric mucosa by blocking lipid peroxidation and scavenging endogenous hydroxyl radicals.

    Leaf extracts of A. indica exhibited significant immune-stimulating effects in vivo (Ray et al, 1996). A. indica potentiated the antibody titres following typhoid H. antigen immunization and induced delayed hypersensitivity following administration of tuberculin and DNCB to animals. In human trials, extracts stimulated humoral immunity by increasing antibody levels and cell-mediated immunity by increasing total lymphocyte and T-cell count in 21 days (Ansari et al., 1997). Aqueous leaf extract was found to lower raised levels of serum liver enzymes and paracetamol-induced liver necrosis (Bhanwra et al., 2000).

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