Vernonia amygdalina (Bitter leaf) – 250g
Original price was: ₵35.00.₵30.80Current price is: ₵30.80.
Sold By: GMF StoreBitter leaf consists of the fresh or dried leaves of Vernonia amygdalina .A shrub or small tree, 2-5 m high with striate pubescent branches, becoming glabrous on maturity; leaves alternate, obovate-lanceolate, entire or finely toothed. Bitterleaf is a highly appreciated vegetable in West and Central Africa and can be consumed in various dishes. Leaf decoctions are used to treat fever, malaria, diarrhoea, dysentery, hepatitis and cough, as a laxative and as a fertility inducer. One of the most common medicinal uses of Vernonia amygdalina is as a treatment against intestinal worms including nematodes. In Zimbabwe a root infusion is used to treat sexually transmitted diseases. The bitterness is caused by sesquiterpene lactones (e.g. vernodalin, vernolepin and vernomygdin) and steroid glucosides (vernoniosides). Some of these compounds have significant antiparasitic activity, especially vernodalin and vernonioside B1. Vernolepin showed platelet anti-aggregating properties. Vernodalin and vernomygdin have cytotoxic activity.Aqueous leaf extracts containing the peptides, edotides, have been found to be potent inhibitors of mitogen-activated protein kinases (MAPK), important agents for the growth of breast cancer cells; the anti-oestrogen drug, tamoxifen, is known to be an MAPK modulator (Atanaskova et al., 2002; Mandlekar and Kong, 2001). Leaf extracts showed inhibitory activity against Trichomonas vaginalis (Hakizamungu et al., 1992) and the aqueous leaf extracts caused reductions in blood sugar levels of normoglycaemic and alloxan diabetic rabbits (Akah andOkafor, 1992).
Functions
- constipation.
- Diabetes
- helminthiasis
- Malaria
- Headaches
- upper respiratory tract infections
Dosage
Decoction: boil 40 g of dried leaves per litre of water for 15 minutes; drink 4 teacupfuls three times a day
Precautions for use
Care should be taken in renal and liver disease.
Contraindications
Pregnancy and lactation, gastric ulcer; nephritis,
renal and liver dysfunction
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Clinical data
Administration of a leaf decoction to a 49-year-old female diabetic patient caused her fasting blood sugar level to fall from 242 mg/dl to about 120 mg/dl after 12 weeks, remaining at this level for eight weeks (Addae-Mensah, 1992). A 45-year old hypertensive woman, who had diabetes diagnosed on routine examination had her fasting blood sugar level of 370 mg/dl reduced to 250 mg/dl after one week and continued to fall until it normalized after eleven weeks on immediate administration of B. ferruginea. No medication was prescribed for her hypertension, but her blood pressure fell from 180/90 to 140/90 during the treatment period (Addae-Mensah, 1992; Ampofo, 1977). Aqueous extracts of the leaves were able to normalize the fasting blood glucose levels and helped in eliminating glycosuria of patients with maturity-onset diabetes (Iwu, 1993). -
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Mucuna pruriens (Velvet bean) is an established herbal drug used for the management of male infertility, nervous disorders, and also as an aphrodisiac. It has been shown that its seeds are potentially of substantial medicinal importance. The ancient Indian medical system, Ayurveda, traditionally used Velvet bean, even to treat such things as Parkinson’s disease. Velvet bean has been shown to have anti-parkinson and neuroprotective effects, which may be related to its anti-oxidant activity. It is a good source of L-DOPA as well as anti-diabetic.
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